Effects Of Lifestyle Modification Research Articles

Community-based Descriptive Cross-sectional Study on Prevalence, Clinical Manifestation, Beliefs and Management Approach of Gastroesophageal Reflux Disease (GERD) Among Young Bangladeshi Population

Despite being a common public health problem, there are few population-based research available to learn about the epidemiology and management of gastrointestinal reflux disease (GERD) in Bangladesh. The tenacity of this study was to investigate the prevalence, potential predisposing factors, clinical representation, therapeutic management of GERD among the young Bangladeshi population along with their beliefs regarding the disease. A descriptive cross-sectional study was conducted during 13th June 2022 to 10th December 2022 among 925 individuals (16-35 years of age) from various parts of Bangladesh. A standardized online questionnaire in both English and the local language (Bengali) was utilized to collect all the desired data that were analyzed using either Microsoft Excel 2019 or, IBM SPSS Statistics, v26.0. The prevalence of GERD was 55.7% which was not significantly associated with different sociodemographic parameters. However, family history (Odds ratio (OR) = 2.512), irregular meal (OR = 1.527) and spicy/junk food (OR = 1.495) were significantly associated with GERD prevalence in binary logistic regression analysis. Heart burn (94.0%) and regurgitation (83.3%) were the major symptoms observed and the average number of symptoms was higher in patients with relevant family history (p < 0.0005). Omeprazole (42.5%) was the most used medication to treat GERD followed by other proton pump inhibitors and H2 blockers. Self-medication was practiced by 52.6% of the patients which was associated with duration of treatment (p < 0.0005). The study has found a high prevalence of GERD in Bangladesh. Family history, irregular meal and spicy/junk foods have been identified as potential risk factors and only half the participants had the right belief regarding the effectiveness of lifestyle modification against GERD. Further cohort studies are advised to solidify the findings of this study. Bangladesh Pharmaceutical Journal 27(1): 19-36, 2024 (January)

Effects of Life Style Modifications (Dietary and Exercise) on Insulin Resistance in Egyptian Men with Impaired Glucose Tolerance

Insulin resistance (IR) is considered one of the most serious chronic conditions. Although IR usually starts silently (euglycemic state), it can seriously lead to impaired glucose tolerance and the development of diabetes mellitus (DM) with other debilitating complications. The current study was conducted for four months to test the application of healthy dietary modification and/or regular programmed exercise on 120 Egyptian male subjects with high blood glucose levels, high insulin levels, and high homeostatic model assessment of insulin resistance (HOMA-IR). They were assigned into 4 groups. The first group received no intervention (control). The second group received healthy dietary intervention. The third group received regular exercise program. The fourth group received both healthy dietary intervention and regular exercise program. Along with blood glucose and insulin levels; weight and triglycerides (TG) levels were also assessed. Compared to the control group, the results showed significant reduction (p˂0.05) in both fasting and postprandial blood glucose and insulin levels as represented by HOMA-IR along with significant reduction (p˂0.05) in the other metabolic parameters assessed during the study in both dietary intervention alone and exercise intervention alone groups. The reduction was more significant (p˂0.05) in the group that received both healthy dietary and regular exercise intervention. In conclusion; IR could be avoided if either healthy dietary modification and/or regular programmed exercise are adopted.

The Effect of Lifestyle Modification on the Recovery of Non-Alcoholic Fatty Liver Disease in Health Insurance Staff in Tabriz, Iran: A Randomized Clinical Trial

The Effect of Lifestyle Modification on the Recovery of Non-Alcoholic Fatty Liver Disease in Health Insurance Staff in Tabriz, Iran: A Randomized Clinical Trial

Effect of Lifestyle Modifications on Reproductive Function among Infertile Obese Women with Polycystic Ovarian Syndrome

Effect of Lifestyle Modifications on Reproductive Function among Infertile Obese Women with Polycystic Ovarian Syndrome

Lifestyle Medicine as a Treatment for Resistant Hypertension.

Approximately 10% of the adults with hypertension fail to achieve the recommended blood pressure treatment targets on 3 antihypertensive medications or require ≥ 4 medications to achieve goal. These patients with 'resistant hypertension' have an increased risk of target organ damage, adverse clinical events, and all-cause mortality. Although lifestyle modification is widely recommended as a first-line approach for the management of high blood pressure, the effects of lifestyle modifications in patients with resistant hypertension has not been widely studied. This review aims to provide an overview of the emerging evidence on the benefits of lifestyle modifications in patients with resistant hypertension, reviews potential mechanisms by which lifestyles may reduce blood pressure, and discusses the clinical implications of the recent findings in this field. Evidence from single-component randomized clinical trials demonstrated that aerobic exercise, weight loss and dietary modification can reduce clinic and ambulatory blood pressure in patients with resistant hypertension. Moreover, evidence from multi-component trials involving exercise and dietary modification and weight management can facilitate lifestyle change, reduce clinic and ambulatory blood pressure, and improve biomarkers of cardiovascular risk. This new evidence supports the efficacy of lifestyle modifications added to optimized medical therapy in reducing blood pressure and improving cardiovascular risk biomarkers in patients with resistant hypertension. These findings need to be confirmed in larger studies, and the persistence of benefit over extended follow-up needs further study.

Effect of lifestyle modification on hepatocellular carcinoma incidence and mortality among patients with chronic hepatitis B

Effect of lifestyle modification on hepatocellular carcinoma incidence and mortality among patients with chronic hepatitis B

Comprehensive effects of lifestyle reform, adherence, and related factors on hypertension control: A review.

Despite the effectiveness of currently available antihypertensive medications, there is still a need for new treatment strategies that are more effective in certain groups of hypertensive and for additional resources to combat hypertension. However, medication non-adherence was previously recognized as a major problem in the treatment of hypertension. The mechanisms behind the positive impacts of lifestyle changes might occur in different ways. In comparison with other studies, the efficacy and effectiveness of lifestyle modifications and antihypertensive pharmaceutical treatment for the prevention and control of hypertension and concomitant cardiovascular disease have been demonstrated in randomized controlled trials. However, in this review, the attitudinal lifestyle modifications and barriers to blood pressure control were elaborated on. An effective method for reducing blood pressure (BP) and preventing cardiovascular events with antihypertensive medications has been outlined. Maintaining healthy lifestyle factors (body mass index, diet, smoking, alcohol consumption, sodium excretion, and sedentary behavior) could lower systolic blood pressure BP by 3.5 mm Hg and reduce the risk of cardiovascular disease (CVD) by about 30%, regardless of genetic susceptibility to hypertension. Conducting a lifestyle intervention using health education could improve lifestyle factors, such as reducing salt, sodium, and fat intake, changing eating habits to include more fruits and vegetables, not smoking, consuming less alcohol, exercising regularly, maintaining healthy body weight, and minimizing stressful conditions. Each behavior could affect BP by modulating visceral fat accumulation, insulin resistance, the renin-angiotensin-aldosterone system, vascular endothelial function, oxidative stress, inflammation, and autonomic function. Evidence of the joint effect of antihypertensive medications and lifestyle reforms suggests a pathway to reduce hypertension.

Results of lifestyle modification promotion and reproductive/general health check for male partners of couples seeking conception

PurposeMale infertility is partially caused by an inappropriate lifestyle and comorbidities. In this study, we analyzed the prevalence of these factors and the effects of lifestyle modifications as part of male preconception care. MethodsFour hundred and two male partners of couples seeking conception with abnormal parameters upon the first semen analysis were enrolled. They were advised to modify their inappropriate lifestyle as male preconception care. Afterward, their general and male reproductive health was examined. Semen quality was compared before and after the promotion. ResultsSmoking, chronic alcohol use, and genital heat stress were found in 22.6%, 47.0%, and 75.1% of patients, respectively. Palpable varicoceles, hypogonadism, obesity (body mass index ≧30 kg/m2), hypertension, zinc deficiency, hyperlipidemia, liver dysfunction, and diabetes mellitus were found in 25.9%, 17.0%, 7.0%, 14.9%, 16.2%, 37.0%, 26.9% and 3.4% of the participants, respectively; 98.8% of the patients had at least one factor. After the promotion, semen parameters and sperm DNA fragmentation were improved significantly. Improvement was found in those with palpable varicocele or hypogonadism but not in those with night work shift, abstinence (>3 days), erectile dysfunction, hypertension, obesity, zinc deficiency, or diabetes mellitus. ConclusionsComorbidities and inappropriate lifestyle choices were common among men with infertility. The promotion of lifestyle modifications as part of male preconception care could improve semen quality without urologic intervention.

Effect of Lifestyle Modification Upon Dysmenorrhea and Pain Severity in University Students of Karachi- Prospective Study

Aim: To evaluate the effect of lifestyle modification upon dysmenorrhea and pain severity in university students of Karachi. Methodology: This is a prospective cohort study, the sample size was 383 participants, and data was collected from the Karachi institute of health sciences. Participants were followed after lifestyle modifications, weight reduction, stress management, physical exercise, and nutrition. Menstruation pain severity was measured by pain visual analog scale score (VAS) score, after 4 weeks and 8 weeks of modification follow-up, participants were asked to fill a validated questionnaire including pain VAS score again to assess the difference in dysmenorrhea and its associated symptoms. Results: Out of 383 study participants, the mean age was 22.2±1.9 years while the mean weight was 72.9±4.7 years, mean age of menarche was 13.4±0.7 years. Pain VAS score was categorized within mild and tolerable, moderate and Uncomfortable, and severe with an immediate need for medical intervention, indicating 82(21.4%), 195(50.9%) and 106(27.6%) frequencies respectively. The effect of lifestyle modification afterthe first menstruation cycle questionnaire was filled again, and results indicated mild, moderate, and severe results as 277(72.3%), 90(23.4%) and 16(4.1%) while on the second cycle 343(89.5%), 34(8.8%) and 6(1.5%) were identified respectively. Conclusion: Lifestyle modification, maintaining a healthy weight, having proper nutrition, and managing stress can sufficiently reduce the chances of dysmenorrhea and decreases the severity of menstrual pain. Keywords:Dysmenorrhea, Pain-vas score, lifestyle modification

17 - The effects of lifestyle modification on semen parameters and oxidative stress. A randomised, controlled interventional study

17 - The effects of lifestyle modification on semen parameters and oxidative stress. A randomised, controlled interventional study

Comparative analysis of effect of life style modification with and without isoflavones for menopausal symptoms

Background: Natural or spontaneous menopause is a transition period in a woman's life from the reproductive to the non-reproductive phase. It happens with the final menstrual period, which is known to happen after 12 months of amenorrhea with no obvious pathological or physiological causes.1,2 It promotes aging and hastens the progression of non-communicable diseases. Menopause occurs between the ages of 45 and 55 worldwide.2 Menopause symptoms manifest not only in the female genital tract, but also in the skeletal, cardiovascular, and psychological systems. With rising life expectancy, women are more likely to experience long periods of menopause, accounting for roughly one-third of their age. As a result, the morbidity burden has increased. Aim and Objectives: To compare the effects of lifestyle modification with & without isoflavones supplementation for menopausal symptoms. Methods: The study was conducted in Department of Obstetrics and Gynaecology, Upper India Sugar Exchange Maternity Hospital, GSVM Medical College in Kanpur of Uttar Pradesh state. This hospital is a tertiary care teaching hospital. The study was conducted in obstetrics department of the hospital. Postmenopausal women who had at least 1 year history of cessation of menses were included. Availability of subjects for the entire study period and willingness to adhere to protocol requirements as evidence by written informed consent. Perimenopausal females of age >40 years. Perimenopausal is the period immediately prior to and up to 1 year after the final menstrual period. Conclusion: The present study was a triple arm randomized clinical trials study conducted to determine the comparative analysis of effect of lifestyle modification with and without Isoflavanis for menopausal symptoms was performed at the department of Obstetrics and gynaecology, Upper India Sugar Exchange Maternity Hospital, GSVM Medical College, Kanpur. The following are the important conclusion drawn from the study. In our study majority of the women were 50 - 69 years age group from urbon population and housewives in occupation in all three groups respectively. In our study majority of the patients had normal BMI and blood pressure in all groups Isoflavanis life style modification and lifestyle Isoflavanis respectively. In our study Vasomotor symptoms psychological and urogenital symptoms reduce after the lifestyle dietary and yoga with Isoflavane and intervention which is shown by reduction in MRS score after the intervention. The results of the present study strongly recommend lifestyle modification dietary supplementation yoga and Isoflavane supplementation resulted in reduction of menopausal symptoms. Thus importance of life-style management yoga and Isoflavane to be incorporated in daily routine under the supervision and motivation / adherence can be mandatory. The mean, Vasomotor symptoms were significantly lower in lifestyle mod which Isoflavane group III group at 2nd visit and 3rd visit. In our study regarding the safety profile of phyto-estrogen Isoflavane no majoride effect, were found and only minor side effect like headache, nausea, vomiting were present. No breakthrough bleeding (every women with hormone therapy).

Effectiveness of Lifestyle Modification on Endometriosis Symptoms among Reproductive Age Women

Effectiveness of Lifestyle Modification on Endometriosis Symptoms among Reproductive Age Women

Effect of Life Style Modification on the health status for Patients with Ulcerative Colitis

Effect of Life Style Modification on the health status for Patients with Ulcerative Colitis

The Effect of Lifestyle Modification on Lipid Profile and Body Weight in Obese Subject

Background. The lifestyle modification (LSM) programs program addresses diet, exercise, stress management, and nutritional depletion using cognitive-behavioral approaches to improve the causes of chronic disease. The purpose of the study is to evaluate the effect before and after three months of LSM on lipid profile and body weight parameters of obese subjects Method. The participants of age 25-50 years recruited through personal contact consisted of 20 obese subjects who appeared to engage in diet and regular exercise (get at least 150 minutes of exercise a week). The types of physical exercise aerobic (walking, swimming, jogging) were included in the study. The anthropometric measurements and blood sample was taken before and after three months of LSM. Height (m) is measured using a wall-mounted height bar and body weight (kg) is measured using a scale and its value is used in BMI calculations. The serum of profile lipid was determined by enzymatic colorimetric method and sd-LDL examination was performed indirectly in which the ratio of LDL /Apolipoprotein B.                                                     Result. After 3 months of LSM, there was a significant decrease in serum LDL, ApoB, BMI, WC, and FPG (p < 0.05) in the obese subject. However, no significant difference was observed in TG, HDL, sd-LDL, PPG, and HbA1C (p>0.05).                        Conclusion. Lifestyle modification of obese subjects for three months can decrease parameters of body weight and profiles lipids, which means it can prevent cardiovascular diseases.

Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome in Women: Effects of Lifestyle Modifications.

Non-alcoholic fatty liver disease (NAFLD) is the most widespread liver disease, characterized by fatty acids liver accumulation and subsequent fibrosis. NAFLD prevalence ranges from 80% to 90% in obese subjects and is estimated to be around 50% in patients with metabolic syndrome. In this clinical scenario, diet and lifestyle modifications can play an important role. There are several imaging techniques that can accurately diagnose fatty liver. Recently, ultrasound has acquired a leading role in the diagnosis and follow-up of fatty liver disease. Furthermore, elastosonography represents a valid alternative to liver biopsy. Shear wave elastosonography evaluates the elastic and mechanical properties of liver tissue. The aim is to evaluate the effects of lifestyle and nutritional interventions and a loss of body weight during hepatic steatosis through ultrasonographic and elastosonographic techniques. Thirty-two female subjects with metabolic syndrome were subjected to clinical, anthropometric, and laboratory assessments, as well as abdominal ultrasonographic/elastosonographic measurements taken from enrollment time (T0) and after 3 months (T1) of lifestyle modifications. After 3 months of lifestyle changes, significant weight loss was observed, with a marked improvement in all adiposity indices. The laboratory parameters at T1 showed significant decreases in total and LDL cholesterol, triglycerides, basal blood glucose, 120 min glycaemia, basal insulin and HOMA Index (p < 0.001). A similar improvement was observed at T1 for steatosis degree (p < 0.01) and elastosonographic measurements (Kpa p < 0.001). The linear regression analysis of the baseline conditions documented that the size of the liver positively correlated with body weight, BMI, neck and waist circumferences, waist to height ratio (WhtR), insulin and HOMA Index, fat mass and visceral fat, and steatosis grade. After 3 months, the liver size showed improvement with positive correlations to all previous variables. Hepatic stiffness (Kpa) positively correlated with neck circumference, visceral fat, and ALT, with basal insulin, gamma-GT, and AST, and with waist circumference, WhtR, and fat mass. The degree of steatosis was positively correlated with more variables and with greater statistical significance at T1 with respect to T0. Particularly, the positive correlations between the degree of steatosis and neck circumference (p < 0.001), HOMA Index, and triglycerides (p < 0.001) appeared to be very significant. NAFLD management in women with metabolic syndrome should be focused on lifestyle modifications. Moreover, liver involvement and improvement at follow-up could be evaluated in a non-invasive manner through ultrasonographic and elastosonographic techniques.

Effectiveness of Lifestyle Modification in Polycystic Ovary Syndrome Patients with Obesity: A Systematic Review and Meta-Analysis.

(1) Background: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility and endocrine disorders among women of reproductive age. Previous studies have employed lifestyle interventions to manage anovulatory infertility and endocrine disorders. However, the effect of lifestyle interventions on the metabolic index remains ambiguous; (2) Methods: Data were obtained through a systematic search of the Ovid-Medline, Ovid-EMBASE, and Cochrane Library databases. Two reviewers independently reviewed the literature in two stages. A consensus was achieved through discussions regarding the final selection of the literature; (3) Results: This study observed that the group that underwent lifestyle modifications displayed significant improvement in reproductive function compared to the control group. Combination therapy with diet and exercise resulted in improved fasting insulin levels, compared to monotherapy with diet or exercise. Moreover, moderate weight loss (a minimum of 5%) resulted in an improved metabolic index. The subgroup analysis revealed that the group that underwent lifestyle modifications had a significantly higher number of patients with improved menstrual cycles, compared to the control groups; (4) Conclusions: Lifestyle modification using combination therapy is a promising therapeutic approach that can be employed in the management of PCOS patients with obesity. This scenario warrants further studies with larger sample sizes to develop ideal treatment protocols.

Effectiveness of Lifestyle Modification vs. Therapeutic, Preventative Strategies for Reducing Cardiovascular Risk in Primary Prevention-A Cohort Study.

Background: Cardiovascular diseases (CVD) are still the leading cause of death in developed countries. The aim of this study was to calculate the potential for CV risk reduction when using three different prevention strategies to evaluate the effect of primary prevention. Methods: A total of 931 individuals aged 20–79 years old from the Bialystok PLUS Study were analyzed. The study population was divided into CV risk classes. The Systematic Coronary Risk Estimation (SCORE), Framingham Risk Score (FRS), and LIFE-CVD were used to assess CV risk. The optimal prevention strategy assumed the attainment of therapeutic goals according to the European guidelines. The moderate strategy assumed therapeutic goals in participants with increased risk factors: a reduction in systolic blood pressure by 10 mmHg when it was above 140 mmHg, a reduction in total cholesterol by 25% when it was above 190 mg/dL, and a reduction in body mass index below 30. The minimal prevention strategy assumed that CV risk would be lowered by lifestyle modifications. The greatest CV risk reduction was achieved in the optimal model and then in the minimal model, and the lowest risk reduction was achieved in the moderate model, e.g., using the optimal model of prevention (Model 1). In the total population, we achieved a reduction of −1.74% in the 10-year risk of CVD death (SCORE) in relation to the baseline model, a −0.85% reduction when using the moderate prevention model (Model 2), and a −1.11% reduction when using the minimal prevention model (Model 3). However, in the low CV risk class, the best model was the minimal one (risk reduction of −0.72%), which showed even better results than the optimal one (reduction of −0.69%) using the FRS. Conclusion: A strategy based on lifestyle modifications in a population without established CVD could be more effective than the moderate strategy used in the present study. Moreover, applying a minimal strategy to the low CV risk class population may even be beneficial for an optimal model.

The effectiveness of lifestyle modification on improving the typology of integration and pathology of women in the family

The effectiveness of lifestyle modification on improving the typology of integration and pathology of women in the family

Effect of Lifestyle Modification on Relieving Constipation Symptoms among Patients with Liver Cirrhosis

Effect of Lifestyle Modification on Relieving Constipation Symptoms among Patients with Liver Cirrhosis

Metabolic syndrome and the risk of kidney diseases: the impact of life style modification

Background: The relationship between metabolic syndrome (MetS) and chronic kidney disease (CKD) is complex and bidirectional. However, the etiological role of MetS in CKD is less clear. Objective: To assess the impact of the MetS on the kidney function using new renal biomarkers, and to study the effect of life style modification by following a balanced hypocaloric diet and increasing physical activity. Subjects and Methods: Eighty seven obese women were enrolled in this study. The MetS criteria were studied which included from 0 to 5 components. Life style changes were performed for eight weeks by following a low caloric balanced diet, and increasing their physical activity. Renal biomarkers were estimated before and after intervention. Results: About 65.5% of the obese volunteers were suffering from MetS, about 37% of them were complaining of renal symptoms. Higher consumption rate of high caloric diet and lower consumption rate of protein, vegetables and fruits were detected among obese metabolic patients compared to obese control. Improvement of all the MetS criteria and the biochemical renal markers were detected after intervention. Conclusion: The MetS raises the risk of CKD. A change in the lifestyle, by including a low calorie healthy diet and increasing physical activity is necessary. Cystatin C/ Beta-trace protein (CysC/ BTP) proved to be good promising biomarkers for detection of early changes in renal functions and defining better tools for prevention, early diagnoses and follow up.